Eczema, also known as dermatitis, is a very common skin condition. There are several different types of eczema, affecting people throughout their lifespan. General practice nurses (GPNs) will see children and adults with eczema regularly and they are well placed to assess, manage and support them. Eczema is a chronic conditon and can have devasting effects on quality of life and mental health. GPNs can play an important role in supporting patients with eczema and their families in understanding how to self-manage this long-term conditon and help with coping strategies. This article outlines eczema as a long-term condition and provides practical advice for GPNs on assessment and treatment in primary care. Psychological effects and intervention and referral guidelines for eczema are also discussed.