Here, Callum Metcalfe-O’Shea, advanced nurse practitioner diabetes specialist and co-chair for the Norfolk Health Professionals Diabetes Forum, looks at how remission in type 2 diabetes can be achieved in some cases. Definitions of remission are explored as well as the challenges patients may face. Dietary advice and pharmacological interventions are considered to help general practice nurses (GPNs) structure their approach in achieving remission for suitable patients with type 2 diabetes.