Atopic eczema is becoming more prevalent across all age groups. It is a condition that occurs in childhood and can resurface or develop for the first time in later life in those who may/may not have previously had asthma or hayfever. Other forms of eczema, such as asteatotic eczema (where the skin is abnormally dry) and varicose eczema (which affects the lower limbs and is common alongside varicose veins), often develop in older people, while irritant or allergic contact dermatitis can develop as a result of occupational activities or hobbies which involve contact with disinfectants or petroleum products. Management of atopic eczema involves leave-on topical creams in mild cases, to the use of systemic immunosuppressive medication in severe cases. However, understanding environmental factors and physiological changes that can occur in atopic eczema, and which can affect the severity of the condition, can assist general practice nurses (GPNs) to eliminate or reduce patients’ exposure, thus improving the control of the condition and reducing the risk of exacerbations.