The number of patients with venous leg ulcers is growing as the population ages. Recent estimates indicate that 730,000 people with venous leg ulcers were treated in 2012/13 (Guest et al, 2015); a number that is predicted to increase year on year. Venous leg ulcers can be difficult to manage in some patients despite best practice, particularly in those with multiple comorbidities. These patients can develop chronic ulceration that can be present for months or even years in some cases. The cost of managing these patients presents a significant burden to the NHS. An evaluation was carried out to determine the efficacy of LQD® wound spray, a unique spray-on wound dressing that contains Chitosan FH02™, in promoting wound healing in patients with longstanding venous leg ulcers. The results indicated that LQD wound spray contributed to putting the wounds onto a healing trajectory.