The purpose of this article is not to discuss the pathophysiology of pain in detail, but to focus on the clinical importance of assessing and managing leg ulcer pain. Effective pain management is crucial for improving patient comfort, promoting wound healing and improving overall quality of life. The article explores how to assess pain, including the importance of understanding a patient’s pain experience, use of pain scales, and distinguishing between different types of pain. It also discusses pharmacological approaches to pain relief and offers suggestions as to how healthcare professionals can minimise pain during dressing changes, a frequent source of distress for patients with leg ulcers.